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The Cutting-Edge Science Behind SystemAge™

SystemAge uses 20 years of research by Dr. Irina Conboy to measure aging with organ-level precision with AI-powered Epigenetics.

Entropy Curve

BioNoise™

Biological Age

Where science meets longevity

The Gold Standard in Biological Age Testing

Clinically validated. Head-to-head tested.

Proven Accuracy Outperforming Competition

See how SystemAge stacks up in direct comparisons against traditional biological age clocks— and why doctors are standing behind it.

Accuracy
Confidence (MMC)
Specificity (TNR)
Sensitivity
Negative Predictive Value (NPV)
F1-score (Best Metric for Clinical Balance)
SystemAge™
0.99
0.97
0.983
0.994
0.986
0.993
DunedinPACE
0.58
0.16
0.584
0.576
0.537
0.586
PhenoAge
0.57
0.14
0.573
0.568
0.568
0.571

Backed by World-Leading Scientists and Clinicians

Our science is backed by world-renowned scientists with cutting-edge research.

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Dr. Irina Conboy

CSO & Co-founder

Leading expert in aging research and regenerative biology. Dr. Conboy's groundbreaking work in cellular rejuvenation and aging mechanisms forms the foundation of our technology.

Dr. Conboy on Google Scholar →

Published Research

Our research has been published in leading journals and featured extensively in the media.

GeroScience

GeroScience - Jan 18, 2025

DNA methylation clocks struggle to distinguish inflammaging from healthy aging, but feature rectification improves coherence and enhances detection of inflammaging

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PubMed

PubMed - Dec 11, 2024

The dominance of old blood, and age-related increase in protein production and noise

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Aging

Aging - Sep 12, 2023

Fail-tests of DNA methylation clocks, and development of a noise barometer for measuring epigenetic pressure of aging and disease

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Cell Cycle

Cell Cycle - Jun 15, 2012

Heterochronic parabiosis for the study of the effects of aging on stem cells and their niches

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Cell Stem Cell

Cell Stem Cell - Jan 10, 2008

A Temporal Switch from Notch to Wnt Signaling in Muscle Stem Cells Is Necessary for Normal Adult Myogenesis

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Nature

Nature - Feb 17, 2005

Rejuvenation of aged progenitor cells by exposure to a young systemic environment

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Trusted by authorities in longevity science

Backed by World-Leading Scientists with Cutting-Edge Research

Experience the science

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